Non‐genetic and genetic rewiring underlie adaptation to hypomorphic alleles of an essential gene-Reference-Cited by-同舟云学术

Non‐genetic and genetic rewiring underlie adaptation to hypomorphic alleles of an essential gene

Published:2021-09-15 Issue:21 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Targa Altea¹²³^ORCID,Larrimore Katherine E¹²,Wong Cheng Kit¹^ORCID,Chong Yu Lin¹²,Fung Ronald¹,Lee Joseph⁴^ORCID,Choi Hyungwon⁴^ORCID,Rancati Giulia¹²³

Affiliation:

1. Institute of Medical Biology (IMB) Agency for Science, Technology and Research (A*STAR) Singapore Singapore

2. Skin Research Institute of Singapore (SRIS) Agency for Science, Technology and Research (A*STAR) Singapore Singapore

3. School of Biological Sciences Nanyang Technological University Singapore Singapore

4. Department of Medicine Yong Loo Lin School of Medicine NUS and National University Health System Singapore Singapore

Funder

National Research Foundation Singapore

National Medical Research Council

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2021107839

Reference56 articles.

1. Undermining the Baldwin Expediting Effect: Does Phenotypic Plasticity Accelerate Evolution?

2. A Hypomorphic Allele in the FGF8 Gene Contributes to Holoprosencephaly and Is Allelic to Gonadotropin-Releasing Hormone Deficiency in Humans

3. Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins

4. Principles and mechanisms of non-genetic resistance in cancer

5. The predictability of molecular evolution during functional innovation

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