Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides-Reference-Cited by-同舟云学术

Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides

Published:2021-05-12 Issue:13 Volume:40 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Lafarga Vanesa¹,Sirozh Oleksandra¹,Díaz‐López Irene²,Galarreta Antonio¹^ORCID,Hisaoka Misaru³⁴,Zarzuela Eduardo⁵,Boskovic Jasminka⁶,Jovanovic Bogdan³⁴,Fernandez‐Leiro Rafael⁷^ORCID,Muñoz Jaime⁵,Stoecklin Georg³⁴^ORCID,Ventoso Iván²,Fernandez‐Capetillo Oscar¹⁸^ORCID

Affiliation:

1. Genomic Instability Group Spanish National Cancer Research Centre (CNIO) Madrid Spain

2. Centro de Biología Molecular ‘Severo Ochoa’ (CSIC‐UAM) Departamento de Biología Molecular Universidad Autónoma de Madrid (UAM) Madrid Spain

3. Division of Biochemistry Mannheim Institute for Innate Immunoscience (MI3) Medical Faculty Mannheim Heidelberg University Mannheim Germany

4. Center for Molecular Biology of Heidelberg University (ZMBH) German Cancer Research Center (DKFZ) DKFZ‐ZMBH Alliance National Center for Tumor Diseases (NCT) Heidelberg Germany

5. ProteoRed‐ISCIII Proteomics Unit Spanish National Cancer Research Centre (CNIO) Madrid Spain

6. Electron Microscopy Unit Spanish National Cancer Research Centre (CNIO) Madrid Spain

7. Genomic Integrity and Structural Biology Group Spanish National Cancer Research Centre (CNIO) Madrid Spain

8. Science for Life Laboratory Division of Genome Biology Department of Medical Biochemistry and Biophysics Karolinska Institute Stockholm Sweden

Funder

H2020 European Research Council

Ministerio de Ciencia, Innovación y Universidades

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2019103311

Reference53 articles.

1. Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

2. The protamine family of sperm nuclear proteins

3. Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

4. Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine

5. Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents

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