Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state-Reference-Cited by-同舟云学术

Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state

Published:2017-01 Issue:1 Volume:13 Page:905
ISSN:1744-4292
Container-title:Molecular Systems Biology
language:en
Short-container-title:Mol Syst Biol

Author:

Fallahi‐Sichani Mohammad¹^ORCID,Becker Verena¹,Izar Benjamin²³,Baker Gregory J¹,Lin Jia‐Ren⁴,Boswell Sarah A¹^ORCID,Shah Parin²^ORCID,Rotem Asaf²^ORCID,Garraway Levi A²³⁵,Sorger Peter K¹⁴⁵^ORCID

Affiliation:

1. Department of Systems Biology Program in Therapeutic Sciences Harvard Medical School Boston MA USA

2. Department of Medical Oncology Dana–Farber Cancer Institute Boston MA USA

3. Broad Institute of Harvard and MIT Cambridge MA USA

4. HMS LINCS Center and Laboratory of Systems Pharmacology Harvard Medical School Boston MA USA

5. Ludwig Center at Harvard Harvard Medical School Boston MA USA

Funder

National Institutes of Health

National Cancer Institute

Life Sciences Research Foundation

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Melanoma Research Alliance

Dana-Farber Cancer Institute

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/msb.20166796

Reference60 articles.

1. Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3

2. Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

3. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

4. Genomic Classification of Cutaneous Melanoma

5. Dynamic Proteomics of Individual Cancer Cells in Response to a Drug

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