Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease

Author:

Bader Jakob M1ORCID,Geyer Philipp E12ORCID,Müller Johannes B1ORCID,Strauss Maximilian T1ORCID,Koch Manja3ORCID,Leypoldt Frank45,Koertvelyessy Peter67,Bittner Daniel6,Schipke Carola G8,Incesoy Enise I9,Peters Oliver910,Deigendesch Nikolaus11,Simons Mikael1213,Jensen Majken K314,Zetterberg Henrik15161718,Mann Matthias12ORCID

Affiliation:

1. Department of Proteomics and Signal Transduction Max Planck Institute of Biochemistry Martinsried Germany

2. NNF Center for Protein Research Faculty of Health Sciences University of Copenhagen Copenhagen Denmark

3. Departments of Nutrition & Epidemiology Harvard T.H. Chan School of Public Health Boston MA USA

4. Institute of Clinical Chemistry Faculty of Medicine Kiel University Kiel Germany

5. Department of Neurology Faculty of Medicine Kiel University Kiel Germany

6. Department of Neurology Medical Faculty Otto von Guericke University Magdeburg Magdeburg Germany

7. Department of Neurology Charité Universitätsmedizin Berlin Berlin Germany

8. Experimental & Clinical Research Center (ECRC), Charité – Universitätsmedizin Berlin corporate member of Freie Universität Berlin Humboldt‐Universität zu Berlin, & Berlin Institute of Health Berlin Germany

9. Department of Psychiatry corporate member of Freie Universität Berlin, Humboldt‐Universität zu Berlin & Berlin Institute of Health, Charité Universitätsmedizin Berlin Berlin Germany

10. German Center for Neurodegenerative Diseases Berlin Germany

11. Institute of Medical Genetics and Pathology University Hospital Basel Basel Switzerland

12. German Center for Neurodegenerative Diseases (DZNE) Munich Germany

13. Munich Cluster for Systems Neurology Munich Germany

14. Department of Public Health University of Copenhagen Copenhagen Denmark

15. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology the Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden

16. Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden

17. UK Dementia Research Institute at UCL London UK

18. Department of Neurodegenerative Disease UCL Institute of Neurology London UK

Funder

Novo Nordisk Fonden

Horizon 2020 Framework Programme

Deutsche Forschungsgemeinschaft

European Research Council

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

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