Long‐term expanding human airway organoids for disease modeling

Author:

Sachs Norman1,Papaspyropoulos Angelos1,Zomer‐van Ommen Domenique D2,Heo Inha1,Böttinger Lena1,Klay Dymph3,Weeber Fleur4,Huelsz‐Prince Guizela5,Iakobachvili Nino6,Amatngalim Gimano D2,Ligt Joep7ORCID,Hoeck Arne7ORCID,Proost Natalie8,Viveen Marco C7,Lyubimova Anna1,Teeven Luc1,Derakhshan Sepideh2,Korving Jeroen1,Begthel Harry1,Dekkers Johanna F1,Kumawat Kuldeep2,Ramos Emilio9,Oosterhout Matthijs FM3,Offerhaus G Johan7,Wiener Dominique J1,Olimpio Eduardo P5,Dijkstra Krijn K4,Smit Egbert F4,Linden Maarten2,Jaksani Sridevi9,Ven Marieke8,Jonkers Jos8ORCID,Rios Anne C10,Voest Emile E4,Moorsel Coline HM3,Ent Cornelis K2,Cuppen Edwin7ORCID,Oudenaarden Alexander1,Coenjaerts Frank E7,Meyaard Linde2,Bont Louis J2,Peters Peter J6,Tans Sander J5,Zon Jeroen S5,Boj Sylvia F9,Vries Robert G9,Beekman Jeffrey M2,Clevers Hans110ORCID

Affiliation:

1. Oncode Institute Hubrecht Institute‐KNAW and UMC Utrecht Utrecht The Netherlands

2. Wilhelmina Children's Hospital and UMC Utrecht Utrecht The Netherlands

3. St. Antonius Hospital Nieuwegein Nieuwegein The Netherlands

4. The Netherlands Cancer Institute Amsterdam The Netherlands

5. FOM Institute AMOLF Amsterdam The Netherlands

6. Maastricht University Maastricht The Netherlands

7. UMC Utrecht Utrecht The Netherlands

8. Mouse Clinic for Cancer and Aging (MCCA) Preclinical Intervention Unit The Netherlands Cancer Institute Amsterdam The Netherlands

9. Hubrecht Organoid Technology Utrecht The Netherlands

10. Princess Máxima Center for Pediatric Oncology Utrecht The Netherlands

Funder

ZonMw

Human Frontier Science Program

Stand Up To Cancer

KWF Kankerbestrijding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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