A rare case of penile cancer in situ metastasizing to lymph nodes

Abstract

Penile carcinoma in situ, or Queyrat’s erythroplasia, is a rare condition of theglans penis. This lesion has been associated with invasive squamous cell carcinoma;however, metastasis without an invasive component is extremely rare.There have only been 2 documented cases with metachronous metastases.We report a third case in which metastases were diagnosed at presentation. Thepatient was a 51-year-old man who presented with a glans penile lesion andbilateral inguinal masses later determined to be carcinoma in situ with metastasesto the inguinal and pelvic lymph nodes. He subsequently underwent a partialpenectomy and lymphadenectomy followed by adjuvant chemotherapy andradiation. This case is discussed, along with a brief review of the literature.