Spontaneous rupture of adult Wilms’ tumor: A case report and review of the literature

Abstract

Wilms’ tumour is rare in adults, and spontaneous rupture with retroperitoneal hemorrhage as the presenting sign of renal tumour is also uncommon. We present a case of a 20-year-old woman with spontaneous rupture of Wilms’ tumour by describing the course of diagnosis and treatment. The patient underwent an open left radical nephrectomy, and was treated with 18 weeks of adjuvant chemotherapy with vincristine and actinomycin D. The follow-up of 12 months demonstrated no recurrence. We also reviewed the limited number of related reports. These suggest that the preoperative diagnosis of adult Wilms’ tumour is very difficult, and radical nephrectomy and postoperative comprehensive therapy are equally important in the treatment of these patients. Factors of prognosis for adults with Wilms’ tumour include tumour stage, histopathology, and time and type of therapy.