Malignant epitheloid angiomyolipoma of the kidney in a child treated with sunitinib, everolimus and axitinib

Author:

Citak Caglar,Yilmaz Eda Bengi,Yaman Emel,Kaya Simge,Tasinlar Hakan,Arpaci Rabia Bozdogan,Apaydin F. Demir

Abstract

The malignant variant of epithelioid angiomyolipoma (EAML) of the kidney is uncommon, extremely aggressive and behaves like a renal cell carcinoma. We present a case of a 12-year-old male with malignant EAML who was treated according to adult treatment protocols. To our knowledge, axitinib has not been used before in children. We conclude that adult protocols, in this rare case, could be safely used in rare childhood malignancies.

Publisher

Canadian Urological Association Journal

Subject

Urology,Oncology

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Clinical and pathological features of renal epithelioid angiomyolipoma (PEComa): A single institution series;Urologic Oncology: Seminars and Original Investigations;2022-02

2. Renal Epithelioid Angiomyolipoma in Children;Journal of Kidney Cancer and VHL;2021-06-04

3. Everolimus in Invasive Malignant Renal Epithelioid Angiomyolipoma;Frontiers in Oncology;2021-01-26

4. Metastatic epithelioid angiomyolipoma treated with everolimus in a patient receiving hemodialysis: A case report;IJU Case Reports;2019-07-09

5. Evaluation of renal tumors in children;Türk Üroloji Dergisi/Turkish Journal of Urology;2018-06-01

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