Author:
Sivapalan Pradeesh,Eklöf Josefin,Bonnesen Barbara,Tønnesen Louise,Wilcke Torgny,Jensen Jens-Ulrik Stæhr
Abstract
This review highlights key aspects of treating chronic obstructive pulmonary disease (COPD) exacerbation, focusing on the optimisation of systemic corticosteroid and antibiotic use through personalised treatment using biomarkers. Eosinophil-guided therapy reduces corticosteroid usage which might reduce side effects, while procalcitonin-guided therapy contributes to reduced antibiotic consumption. These approaches, documented through well-conducted randomized controlled trials, suggest the possibility of enhancing COPD exacerbation management, reducing potential side effects, and addressing concerns related to antibiotic resistance.
Publisher
Danish Medical Association