Diagnostic utility of the systemic immune-inflammatory index in preterm neonates with late-onset sepsis-Reference-Cited by-同舟云学术

Diagnostic utility of the systemic immune-inflammatory index in preterm neonates with late-onset sepsis

Published:2023-09-29 Issue:3 Volume:36 Page:319-325
ISSN:1019-1941
Container-title:Marmara Medical Journal
language:
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Author:

VARDAR Gonca¹,ÖZEK Eren¹

Affiliation:

1. Marmara University, Department of Child Health and Pediatrics, School of Medicine, Division of Neonatology

Abstract

Objective: To assess if systemic immune-inflammatory index (SII) has a diagnostic role for late-onset sepsis (LOS) in premature neonates. Patients and Methods: A single-center retrospective observational study including preterm infants with culture-proven LOS and controls was conducted between January 2017 and December 2022. SII was derived using complete blood count values acquired at the beginning of and three to five days before LOS. SII was compared between the LOS group and controls. Results: A total of 144 infants were included in the study. The SII values of the LOS group were found to be significantly increased in comparison to the control group [376.74 (11.11 – 15170) vs. 235.24 (46.83 – 1214.38) (median, min-max), P =0.018]. The SII values significantly increased when pre-sepsis and LOS values were compared [200.6 (0 – 1295.78) vs. 328.28 (0 – 14678, P

Publisher

Marmara University

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