Congenital cytomegalovirus infection cases and follow-up findings in Antalya, Turkey-Reference-Cited by-同舟云学术

Congenital cytomegalovirus infection cases and follow-up findings in Antalya, Turkey

Published:2023-09-29 Issue:3 Volume:36 Page:290-296
ISSN:1019-1941
Container-title:Marmara Medical Journal
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Author:

ERES SARITAS Zubeyde¹^ORCID,PEKER Bilal Olcay²^ORCID,ÇOLAK Dilek³^ORCID,SAGLIK Imran⁴^ORCID,SARİNOĞLU Rabia Can⁵^ORCID,TURHAN Murat⁶,BOSTANCI TOPTAŞ Aslı⁶^ORCID,MUTLU Derya³^ORCID,ÖNGÜT Gözde³^ORCID,OYGUR Nihal⁷^ORCID,ERMAN Munire⁸^ORCID

Affiliation:

1. University of Health Sciences, Antalya Training and Research Hospital, Medical Microbiology Laboratory

2. İzmir Katip Çelebi University, Atatürk Traning and Research Hospital, Medical Microbiology Laboratory

3. AKDENİZ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI, VİROLOJİ BİLİM DALI

4. ULUDAG UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF MEDICAL MICROBIOLOGY

5. Marmara University Pendik Training and Research Hospital, Medical Microbiology Laboratory

6. Akdeniz University, Faculty of Medicine, Department of Ear-Nose and Throat Surgey

7. AKDENIZ UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, NEONATOLOGY

8. Akdeniz University, Faculty of Mecidine, Department Obstetrics and Gynecology,

Abstract

Objective: To investigate the presence of cCMV infection and the CMV-DNA virus in the newborns who applied for newborn hearing screening test (NHST) and CMV-DNA viruria with physical, mental-motor development and hearing status of cCMV cases in the second year of age. Patients and Methods: CMV-DNA was investigated in 1150 newborns’ oral swabs (0-21 days) by polymerase chain reaction kit and urine of patients with positive CMV-DNA in saliva. Transient Evoked Otoacoustic Emission test was performed for NHST. Results: CMV-DNA was posititve in saliva of 38 (3.3%) newborns and urine of 10 out of 37 newborns. The prevalence of cCMV was 0.87% (95% CI=0.697-1.042). All newborns passed the NHST. In newborns with cCMV:jaundice in 60% (6/10), low birthweight in 40% (4/10), small for gestational age in 50% (5/10) of them. Jaundice was the most significant variable (P

Publisher

Marmara University

Reference35 articles.

1. Manicklal S, Emery VC, Lazzarotto T, et al. The “silent” global burden of congenital Cytomegalovirus. Clin Microbiol Rev 2013;26:86-102. doi: 10.1128/CMR.00062-12

2. Grosse S, Ross DS, Dollard SC. Congenital Cytomegalovirus infection as a cause of permanent bilateral hearing loss: a quantitative assessment. J Clin Virol 2018;41:57-62. doi: 10.1016/j.jcv.2007.09.004

3. Mussi-Pinhata MM, Yamamoto AY, Moura Brito RM, et al. Birth prevalence and natural history of congenital Cytomegalovirus infection in a highly seroimmune population. Clin Infect Dis 2009;49:522-8. doi: 10.1086/600882.

4. Kenneson A, Cannon MJ. Review and meta-analysis of the epidemiology of congenital Cytomegalovirus (CMV) infection. Rev Med Virol 2007;17:253-76. doi: 10.1002/ rmv.535

5. Ataman S, Colak D, Günseren F, et al. Investigation of Cytomegalovirus seroepidemiology in Antalya with a population-based cross-sectional study and review of related data in Turkey. Mikrobiyol Bul 2007;41:545-55.