Patient Characteristics Can Influence the Incidence of Perioperative Microemboli during Carotid Artery Interventions

Author:

Zayed Mohamed A.12,Hitchner Elizabeth3,Gholibeikian Simin3,Rosen Allyson4,Lane Barton56,Zhou Wei37

Affiliation:

1. Department of Surgery, Section of Vascular Surgery, Washington University School of Medicine, St Louis, MO 63110, USA

2. Department of Surgery, Division of Vascular Surgery, VA St. Louis Health Care System, St. Louis, MO 63106, USA

3. Department of Surgery, Division of Vascular Surgery, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA

4. Department of Psychiatry, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA

5. Department of Radiology, Stanford University, Palo Alto, CA 94305, USA

6. Department of Radiology, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA

7. Department of Surgery, Division of Vascular Surgery, Stanford University, Palo Alto, CA 94305, USA

Abstract

Purpose. Perioperative cerebral microembolization demonstrated on diffusion-weighted MRI (DWI) can occur following carotid endarterectomy (CEA) and carotid artery stenting (CAS). We sought to explore potential risk factors for this in the large patient cohort. Methods. We reviewed a 6-year consecutive patient cohort that received either CEA or CAS, and perioperative DWI evaluations. Results. 303 patients were reviewed, and 56 (19.4%) patients were found to have perioperative microemboli. The incidence was higher among patients who received CAS (P < 0.001). Hypertension (P = 0.03), smoking (P = 0.001), and a history of transient ischemic attacks (P = 0.04) were risk factors for microembolization. The risk was higher among CEA patients with obesity (P = 0.05), and among CAS patients with coronary artery disease (P = 0.03). Conclusion. Specific patient populations are likely more prone to develop perioperative cerebral microemboli following carotid intervention. Continued risk stratification may help decrease future perioperative cerebral microembolization rates.

Publisher

Hindawi Limited

Subject

General Economics, Econometrics and Finance

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