Effects of Electroacupuncture at BL60 on Formalin-Induced Pain in Rats

Author:

Chang Kyung-Ha1,Won Ran2,Shim Insop3,Lee Hyejung3,Lee Bae Hwan1

Affiliation:

1. Department of Physiology and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea

2. Division of Health Science, Department of Biomedical Laboratory Science, Dongseo University, Busan 617-716, Republic of Korea

3. Acupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 130-701, Republic of Korea

Abstract

Acupuncture was used to treat symptoms of pain in the ancient orient. The present study was conducted to determine the effects of electroacupuncture (EA) at the BL60 acupoint on male Sprague-Dawley rats. Each rat received EA at BL60 acupoint before formalin injection. Behavioral responses were recorded using a video camera and c-Fos immunohistochemistry was performed thereafter. Treatment of EA at BL60 significantly inhibited flinching behavior and c-fos expression induced by formalin injection into the paw, compared to a control group. These results suggest that electroacupuncture at BL60 acupoint may be effective in relieving inflammatory pain.

Funder

National Research Foundation of Korea

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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