Clinical Characteristics, Treatment Patterns, and Outcomes of Primary Canaliculitis among Patients in Beijing, China

Author:

Zhang Qin123,Xu Beibei4,Li Xiao-Xin12,Li Ming-Wu12

Affiliation:

1. Department of Ophthalmology, People’s Eye Institute, Peking University People’s Hospital, Beijing 100044, China

2. Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing 100044, China

3. Peking University Center for Human Disease Genomics, Peking University Health Science Center, Beijing 100191, China

4. Peking University Medical Informatics Center, Beijing 100191, China

Abstract

Background. Canaliculitis may cause punctal or canalicular swelling, discharge, erythema, and sometimes concretions. This study examined the clinical characteristics, treatment patterns, and outcomes of primary canaliculitis from patients at a top-rated hospital in Beijing, China.Methods. Medical records of 16 patients (retrospective case series) were studied.Results. This study included four males and twelve females with a median age of 72.5 years. The mean and the median follow-up time were 10.4 months and 6 months, respectively. The mostly observed clinical symptoms were epiphora with discharge (94%), while the mostly observed signs included pouting punctum (75%) and punctal regurgitation of concretions under syringing (75%). Only the symptoms of one patient among those with conservative therapy completely resolved within two-year follow-up. Curettage therapy was found to partly resolve the clinical symptoms and signs within the follow-up of four weeks. Fifteen patients finally received curettage with punctoplasty, and symptoms completely resolved in fourteen patients after one surgery.Conclusions. Syringing with pressing of lacrimal sac area may help better diagnosis of canaliculitis. Additionally, curettage with punctoplasty is recommended for thorough removal of concretions and complete resolution of canaliculitis.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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