Reversed Halo Sign in Tuberous Sclerosis Complex

Author:

Suzuki Kazuhiro1ORCID,Seyama Kuniaki2,Hayashi Takuo3ORCID,Yamashiro Yuki1,Shiraishi Akihiko1,Kuwatsuru Ryohei1

Affiliation:

1. Department of Radiology, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan

2. Department of Respiratory Medicine, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan

3. Department of Human Pathology, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan

Abstract

We describe a reversed halo sign in a teenage girl with tuberous sclerosis complex (TSC). Lung manifestations of TSC include lung cysts corresponding to lymphangioleiomyomatosis and small nodules indicating multifocal micronodular pneumocyte hyperplasia (MMPH). However, a reversed halo sign in TSC has never been reported. The lesion was microscopically consistent with MMPH. Immunohistological findings also supported the notion that the lesion is associated with TSC.

Publisher

Hindawi Limited

Subject

General Medicine

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