Affiliation:
1. Department of Chemistry, Xinxiang Medical University, Xinxiang, Henan 453003, China
2. School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan 453003, China
3. Department of Chemistry, Nankai University, Tianjin 300071, China
Abstract
A simple colorimetric sensor, 2-bromonaphthalene-1,4-dione, has been developed for the Cysteine detection. The sensor showed its best performance in a mixture of ethanol and HEPES (5 : 5, v/v) solution at pH of 7.0. The results of UV-vis and fluorescence indicated that 2-bromonaphthalene-1,4-dione was selective and sensitive for Cysteine detection without the interference of other amino acids (Cysteine, Alanine, Arginine, Aspartinie, Glutamine, Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Proline, Serine, Threonine, Phenylalanine, Valine, Tryptophan, and Hydroxyproline). 2-Bromonaphthalene-1,4-dione also showed binding ability for Cysteine in bovine serum albumin and could be used as a potential colorimetric sensor among eighteen kinds of natural amino acids. Importantly, the recognition of CySH could be observed by naked eye.
Funder
National Natural Science Foundation of China
Subject
Electrical and Electronic Engineering,Instrumentation,Control and Systems Engineering
Cited by
4 articles.
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