Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model-Reference-Cited by-同舟云学术

Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model

Published:2019-12-05 Issue: Volume:2019 Page:1-8
ISSN:0962-9351
Container-title:Mediators of Inflammation
language:en
Short-container-title:Mediators of Inflammation

Author:

Murando Federica¹,Peloso Andrea²³^ORCID,Cobianchi Lorenzo¹⁴

Affiliation:

1. General Surgery Department, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy

2. Hepatology and Transplantation Laboratory, Department of Surgery, Faculty of Medicine, University of Geneva, Geneva, Switzerland

3. Divisions of Abdominal and Transplantation Surgery, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

4. Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy

Abstract

Animal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to help choose the most appropriate model for individual experimental purposes.

Publisher

Hindawi Limited

Subject

Cell Biology,Immunology

Link

http://downloads.hindawi.com/journals/mi/2019/8971036.pdf

Reference52 articles.

1. The Epidemiology of Sepsis in the United States from 1979 through 2000

2. Comparison of two different models of sepsis induced by cecal ligation and puncture in rats

3. Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

4. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sex differences in skin microcirculatory vascular reactivity in experimental lipopolysaccharide-induced endotoxinemia;Regional blood circulation and microcirculation;2024-06-25

2. Effects of NF-κB Inhibitor on Sepsis Depend on the Severity and Phase of the Animal Sepsis Model;Journal of Personalized Medicine;2024-06-17

3. The Chemical and Social Landscape of the Modern World and Increased Risk of ASIA;Autoimmune Disorders;2024-05-03

4. The Role of TRP Channels in Sepsis and Colitis;International Journal of Molecular Sciences;2024-04-27

5. Effects of Mitochondrial Transplantation on Transcriptomics in a Polymicrobial Sepsis Model;International Journal of Molecular Sciences;2023-10-18