Neoadjuvant Treatment in Rectal Cancer: Actual Status-Reference-Cited by-同舟云学术

Neoadjuvant Treatment in Rectal Cancer: Actual Status

Published:2011-09-21 Issue: Volume:2011 Page:1-12
ISSN:2090-2107
Container-title:Chemotherapy Research and Practice
language:en
Short-container-title:Chemotherapy Research and Practice

Author:

Garajová Ingrid¹,Di Girolamo Stefania¹,de Rosa Francesco¹,Corbelli Jody¹,Agostini Valentina¹,Biasco Guido¹,Brandi Giovanni¹

Affiliation:

1. Department of Hematology and Oncology Sciences “L. A. Seragnoli”, Sant'Orsola-Malpighi Hospital, University of Bologna, via Massarenti 9, 40138 Bologna, Italy

Abstract

Neoadjuvant (preoperative) concomitant chemoradiotherapy (CRT) has become a standard treatment of locally advanced rectal adenocarcinomas. The clinical stages II (cT3-4, N0, M0) and III (cT1-4, N+, M0) according to International Union Against Cancer (IUCC) are concerned. It can reduce tumor volume and subsequently lead to an increase in complete resections (R0 resections), shows less toxicity, and improves local control rate. The aim of this review is to summarize actual approaches, main problems, and discrepancies in the treatment of locally advanced rectal adenocarcinomas.

Publisher

Hindawi Limited

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,Oncology

Link

http://downloads.hindawi.com/archive/2011/839742.pdf

Reference111 articles.

1. Management of Early Rectal T1 and T2 Cancers

2. Neoadjuvant Capecitabine and Oxaliplatin Followed by Synchronous Chemoradiation and Total Mesorectal Excision in Magnetic Resonance Imaging–Defined Poor-Risk Rectal Cancer

3. Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study

4. Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer

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