Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication

Author:

Zaarour Mazen1,Hassan Samer2,Thumallapally Nishitha1,Dai Qun2

Affiliation:

1. Department of Medicine, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USA

2. Department of Medicine, Division of Hematology and Oncology, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USA

Abstract

In the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is an uncommon yet life-threatening neurosurgical emergency that can be associated with the use of these agents. Rivaroxaban, one of the newly approved OACs, is a direct factor Xa inhibitor. To the best of our knowledge, to date, only two published cases report the incidence of rivaroxaban-induced nontraumatic spinal subdural hematoma (SSDH). Our case is the third one described and the first one to involve the cervicothoracic spine.

Publisher

Hindawi Limited

Subject

Cell Biology,Developmental Biology,Embryology,Anatomy

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