T Cells in Gastric Cancer: Friends or Foes-Reference-Cited by-同舟云学术

T Cells in Gastric Cancer: Friends or Foes

Published:2012 Issue: Volume:2012 Page:1-10
ISSN:1740-2522
Container-title:Clinical and Developmental Immunology
language:en
Short-container-title:Clinical and Developmental Immunology

Author:

Amedei Amedeo¹²,Della Bella Chiara¹²,Silvestri Elena¹³,Prisco Domenico¹³,D'Elios Mario M.¹²

Affiliation:

1. Patologia Medica, Dipartimento de Biomedicina, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, 50134 Firenze, Italy

2. Department of Internal Medicine, University of Florence, Florence 50134, Italy

3. Department of Medical and Surgical Critical Care, University of Florence, Florence 50134, Italy

Abstract

Gastric cancer is the second cause of cancer-related deaths worldwide.Helicobacter pyloriis the major risk factor for gastric cancer. As for any type of cancer, T cells are crucial for recognition and elimination of gastric tumor cells. Unfortunately T cells, instead of protecting from the onset of cancer, can contribute to oncogenesis. Herein we review the different types, “friend or foe”, of T-cell response in gastric cancer.

Funder

Ministry of University and Research

Publisher

Hindawi Limited

Subject

General Medicine,Immunology,Immunology and Allergy

Link

http://downloads.hindawi.com/journals/jir/2012/690571.pdf

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