Medical Cost Trajectories and Onsets of Cancer and NonCancer Diseases in US Elderly Population

Author:

Akushevich Igor1,Kravchenko Julia2,Akushevich Lucy2,Ukraintseva Svetlana12,Arbeev Konstantin1,Yashin Anatoliy I.12

Affiliation:

1. Center for Population Health and Aging, Duke University, Durham, NC 27708, USA

2. Duke Cancer Institute, Duke University, Durham, NC 27705, USA

Abstract

Time trajectories of medical costs-associated with onset of twelve aging-related cancer and chronic noncancer diseases were analyzed using the National Long-Term Care Survey data linked to Medicare Service Use files. A special procedure for selecting individuals with onset of each disease was developed and used for identification of the date at disease onset. Medical cost trajectories were found to be represented by a parametric model with four easily interpretable parameters reflecting: (i) prediagnosis cost (associated with initial comorbidity), (ii) cost of the disease onset, (iii) population recovery representing reduction of the medical expenses associated with a disease since diagnosis was made, and (iv) acquired comorbidity representing the difference between post- and pre diagnosis medical cost levels. These parameters were evaluated for the entire US population as well as for the subpopulation conditional on age, disability and comorbidity states, and survival (2.5 years after the date of onset). The developed approach results in a family of new forecasting models with covariates.

Funder

National Institute on Aging

Publisher

Hindawi Limited

Subject

Applied Mathematics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modelling and Simulation,General Medicine

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