Simultaneous Nasopharyngeal Carriage of Two Pneumococcal Multilocus Sequence Types with a Serotype 3 Phenotype

Author:

Inverarity Donald1ORCID,Diggle Mathew2,Ure Roisin3,Santana-Hernandez Diego4,Altstadt Peter5,Mitchell Timothy6,Edwards Giles3

Affiliation:

1. Monkland Hospital, Clinical Microbiology Department, Monklands General Hospital, Monkscourt Avenue, Airdrie, Lanarkshire ML5 0JS, UK

2. Queens Medical Centre, Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham NG7 2UH, UK

3. Scottish Haemophilus, Legionella, Meningococcal and Pneumococcal Reference Laboratory (SHLMPRL), Stobhill Hospital, Glasgow G21 3UW, UK

4. Fundación Totaí, Casilla 158, Trinidad, Beni, Bolivia

5. Laboratorios Altstadt, Casilla 158, Trinidad, Beni, Bolivia

6. Institute of Infection, Immunity and Inflammation, Glasgow Biomedical Research Centre University of Glasgow, College of Medical, Veterinary and Life Sciences, 120 University Place, Glasgow G12 8TA, UK

Abstract

Knowledge of the epidemiology of pneumococcal disease in Bolivia is sparse, and Multilocus Sequence Typing (MLST) of isolates has not been previously possible. Beni state has until recently been a geographically isolated region of the Bolivian Amazon basin and is a region of significant poverty. During June and July 2007, we performed a pneumococcal carriage study recruiting over 600 schoolchildren in two towns in the Beni state. Here, we describe the unique identification of simultaneous nasopharyngeal carriage of two pneumococcal multilocus sequence types with a serotype 3 phenotype within a single subject.

Publisher

Hindawi Limited

Subject

Microbiology (medical),Microbiology

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