TCTP in Development and Cancer-Reference-Cited by-同舟云学术

TCTP in Development and Cancer

Published:2012 Issue: Volume:2012 Page:1-9
ISSN:2090-2247
Container-title:Biochemistry Research International
language:en
Short-container-title:Biochemistry Research International

Author:

Koziol Magdalena J.¹^ORCID,Gurdon John B.²

Affiliation:

1. Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA

2. Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK

Abstract

The translationally controlled tumor protein (TCTP) is highly conserved among animal species. It is widely expressed in many different tissues. It is involved in regulating many fundamental processes, such as cell proliferation and growth, apoptosis, pluripotency, and the cell cycle. Hence, it is not surprising that it is essential for normal development and, if misregulated, can lead to cancer. Provided herein is an overview of the diverse functions of TCTP, with a focus on development. Furthermore, we discuss possible ways by which TCTP misregulation or mutation could result in cancer.

Publisher

Hindawi Limited

Subject

Biochemistry

Link

http://downloads.hindawi.com/journals/bri/2012/105203.pdf

Reference91 articles.

1. Transcriptional and translational control of cytoplasmic proteins after serum stimulation of quiescent Swiss 3T3 cells.

2. Messenger RNA species partially in a repressed state in mouse sarcoma ascites cells.

3. Translationally controlled tumor protein is a conserved mitotic growth integrator in animals and plants

4. Expression of the gene and processed pseudogenes encoding the human and rabbit translationally controlled tumour protein (TCTP)

5. Cellular distribution of translationally controlled tumor protein in rat and human testes

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