Therapeutic Effects of Ten Commonly Used Chinese Herbs and Their Bioactive Compounds on Cancers

Author:

Liu Wei12ORCID,Yang Binbin12,Yang Lu12,Kaur Jasmine2,Jessop Calvin2,Fadhil Rushdi2,Good David23ORCID,Ni Guoying2456ORCID,Liu Xiaosong456ORCID,Mosaiab Tamim2,Yi Zhengjun1ORCID,Wei Ming Q.2ORCID

Affiliation:

1. Department of Laboratory Medicine, Key Laboratory of Clinical Laboratory Diagnostics in Universities of Shandong, Weifang Medical University, 261053 Weifang, Shandong, China

2. School of Medical Science & Menzies Health Institute Queensland, Griffith University, Brisbane, Australia

3. School of Allied Health, Australian Catholic University, Brisbane, Australia

4. Cancer Research Institute, Guangdong Pharmaceutical University, Guangzhou, China

5. Inflammation and Healing Research Cluster, Sunshine Coast University, Sunshine Coast, Australia

6. Molecular Diagnosis and Target Therapy Laboratory, Guangzhou, China

Abstract

Effective cancer therapy is one of the biggest global challenges. Conventional cancer therapies have been at the forefront of combating cancers, but more evidence showed considerable side effects, limiting their use. There are various new therapies in development, but combined approaches for treating cancer are much expected. Natural herbs had been traditionally in use for cancer therapy in most parts of the world. In this review, we have examined ten commonly used Chinese herbs that have, for centuries, shown effectiveness in treating cancers. They demonstrated the abilities to promote the apoptosis of cancer cells, inhibit their metastasis, activate the patient’s anticancer immunity, and synergistically increase the efficacy of conventional chemotherapy and radiation therapy when used in combination. Clinical experiences had proved that these herbs and their bioactive compounds were effective against a plethora of cancers through a variety of mechanisms, effectively improving patients’ quality of life without significant side effects. These advantages indicate that there are huge potentials in the development of Chinese herbs into cancer medicine as part of a promising, holistic cancer treatment modality.

Funder

Natural Science Foundation of Shandong Province

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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