Triterpenoid-Rich Extract fromAntrodia camphorataImproves Physical Fatigue and Exercise Performance in Mice

Author:

Huang Chi-Chang1,Hsu Mei-Chich12,Huang Wen-Ching34,Yang Huei-Ru1,Hou Chia-Chung3

Affiliation:

1. Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan

2. Department of Sports Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

3. Dong Jyu Biotechnology Corporation, Taipei 10683, Taiwan, Taiwan

4. Graduate Institute of Athletics and Coaching Science, National Taiwan Sport University, Taoyuan 33301, Taiwan

Abstract

Antrodia camphorata(AC) is an endemic mushroom that grows in Taiwan. We investigated the fatigue-alleviating effects of AC on endurance capacity in swim-exercised and weight-loading mice. Male Institute of Cancer Research (ICR) strain mice from 3 groups (n=10per group in each test) were orally administered AC fruiting body extract for 7 days at 0, 50, and 200 mg/kg/day, designated vehicle, AC-50, and AC-200, respectively. Trend analysis revealed that AC treatments increased grip strength. AC dose-dependently increased swim time, blood glucose, and muscular and hepatic glycogen levels and dose-dependently decreased plasma lactate and ammonia levels and creatine kinase activity. The increase in swimming endurance with AC administration was caused by an increase in liver and muscle glycogen deposition.A. camphoratamay have potential for use in ergogenic and antifatigue activities.

Funder

National Taiwan Sport University, Taoyuan, Taiwan

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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