Ginger for Healthy Ageing: A Systematic Review on Current Evidence of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties

Author:

Ozkur Mehtap1ORCID,Benlier Necla1ORCID,Takan Işıl23ORCID,Vasileiou Christina4ORCID,Georgakilas Alexandros G.4ORCID,Pavlopoulou Athanasia23ORCID,Cetin Zafer56ORCID,Saygili Eyup Ilker78ORCID

Affiliation:

1. Department of Medical Pharmacology, Faculty of Medicine, SANKO University, Gaziantep, Turkey

2. Izmir Biomedicine and Genome Center, Balcova, Izmir 35340, Turkey

3. Izmir International Biomedicine and Genome Institute, Dokuz Eylül University, Balcova, Izmir 35220, Turkey

4. DNA Damage Laboratory, Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens, 157 80 Athens, Greece

5. Department of Medical Biology, School of Medicine, SANKO University, Gaziantep, Turkey

6. Department of Biological and Biomedical Sciences, Graduate Education Institute, SANKO University, Gaziantep, Turkey

7. Department of Medical Biochemistry, School of Medicine, SANKO University, Gaziantep, Turkey

8. Department of Molecular Medicine, Graduate Education Institute, SANKO University, Gaziantep, Turkey

Abstract

The world’s population is ageing at an accelerated pace. Ageing is a natural, physiological but highly complex and multifactorial process that all species in the Tree of Life experience over time. Physical and mental disabilities, and age-related diseases, would increase along with the increasing life expectancy. Ginger (Zingiber officinale) is a plant that belongs to the Zingiberaceae family, native to Southeast Asia. For hundreds of years, ginger has been consumed in various ways by the natives of Asian countries, both as culinary and medicinal herb for the treatment of many diseases. Mounting evidence suggests that ginger can promote healthy ageing, reduce morbidity, and prolong healthy lifespan. Ginger, a well-known natural product, has been demonstrated to possess antioxidant, anti-inflammatory, anticancer, and antimicrobial properties, as well as an outstanding antiviral activity due to a high concentration of antiviral compounds. In this review, the current evidence on the potential role of ginger and its active compounds in the prevention of ageing is discussed.

Publisher

Hindawi Limited

Subject

Cell Biology,Aging,General Medicine,Biochemistry

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