Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases

Author:

Koslow Matthew1ORCID,Maleki-Fischbach Mehrnaz2,Keith Rebecca C.1

Affiliation:

1. Division of Pulmonary, Critical Care and Sleep Medicine, Interstitial Lung Disease Program, National Jewish Health, Denver, CO, USA

2. Division of Rheumatology, National Jewish Health, Denver, CO, USA

Abstract

Interstitial lung disease (ILD) associated with connective tissue diseases (CTDs) is highly heterogeneous in its clinical presentation and course. The diagnosis and management of CTD-ILD require a multidisciplinary approach involving, at minimum, a rheumatologist, a pulmonologist, and a radiologist. Close monitoring of patients with CTD-ILD is important to enable early detection of disease progression and inform decisions regarding the initiation or escalation of pharmacotherapy. In the absence of guidelines regarding how CTD-ILDs should be treated, clinicians face difficult decisions on when to use immunosuppressant and anti-fibrotic therapies. The importance of a multidisciplinary and individualized approach to the diagnosis and management of CTD-ILD is highlighted in the three case studies that we describe in this article.

Funder

Boehringer Ingelheim Pharmaceuticals, Inc.

Publisher

Hindawi Limited

Subject

General Agricultural and Biological Sciences

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