A Rare Case of Stroke Secondary to Iron Deficiency Anemia in a Young Female Patient

Author:

Gopalratnam Kavitha1,Woodson Kevin Andrew1ORCID,Rangunwala Jigarkumar1ORCID,Sena Kanaga1,Gupta Manisha1

Affiliation:

1. Bridgeport Hospital-Yale New Haven Health, 267 Grant St, Bridgeport, CT 06610, USA

Abstract

Ischemic strokes occur when there is a sudden obstruction of an artery supplying blood flow to an area of the brain, leading to a focal neurological deficit. Strokes can be thrombotic or embolic in etiology and are associated with underlying conditions such as hypertension and atherosclerosis. Possible etiologies of strokes include cardioembolic disease, hematologic disorders, connective tissue disorders, and substance abuse or can be cryptogenic. Most stroke cases are seen in patients over 65 years of age. However, about one-fourth of strokes occur in young adults. Iron deficiency anemia (IDA) has been described as a known cause for strokes in children, but very few case reports describe this association in adults. We describe a 20-year-old female who presented with sudden onset left side weakness. Magnetic Resonance Imaging (MRI) of the brain demonstrated ischemic infarctions. Patient was also found to be severely anemic. Patient had a thorough work-up including Magnetic Resonance Angiography (MRA) of the brain, echocardiogram, and an extensive screen for thrombophilia disorders. This, however, did not demonstrate a clear etiology. As it has been suggested that IDA is a potential cause for stroke, it is possible the stroke in this young patient was attributable to severe IDA.

Publisher

Hindawi Limited

Subject

General Medicine

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Iron, ferroptosis, and ischemic stroke;Journal of Neurochemistry;2023-03-27

2. Cerebrovascular Complications of Anemia;Current Neurology and Neuroscience Reports;2021-09-03

3. Cerebro‐renal interaction and stroke;European Journal of Neuroscience;2020-10-17

4. Association between Anemia and Stroke in Females: A Nationwide, Population-Based Cohort Study in Taiwan;International Journal of Environmental Research and Public Health;2020-10-13

5. Acute ischemic stroke as initial manifestation of undiagnosed iron deficiency anemia: case-report and literature review;AME Case Reports;2020-10

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