Investigation of the Immunoprotective Effect of Zinc on Ovalbumin Induced BALB/C Male Mice Based on NF-KB Signaling Pathway-Reference-Cited by-同舟云学术

Investigation of the Immunoprotective Effect of Zinc on Ovalbumin Induced BALB/C Male Mice Based on NF-KB Signaling Pathway

Published:2022-08-08 Issue: Volume:2022 Page:1-7
ISSN:1555-4317
Container-title:Contrast Media & Molecular Imaging
language:en
Short-container-title:Contrast Media & Molecular Imaging

Author:

Shi Qiangyou¹,Shen Xueliang²,Long Chao¹,Guo Fan¹,Mi Zhipeng¹,Li Yongchun²,Ma Ruixia²^ORCID

Affiliation:

1. Ningxia Medical University, Ningxia 750004, China

2. Department of Otolaryngology Head and Neck Surgery, Second Affiliated Hospital of Ningxia Medical University Yinchuan First People’s Hospital, Ningxia 750004, China

Abstract

Allergic rhinitis is one of the common chronic inflammatory diseases of the nasal mucosa. In order to investigate the effect of zinc on ovalbumin induced allergic rhinitis in BALB/C male mice based on NF-KB signaling pathway, thirty BALB/C male mice are randomly divided into three groups: control group, ovalbumin induced allergic rhinitis asthma group and zinc intervention group. The experimental results show that Zinc supplementation in allergic asthma mice with allergic rhinitis correct the immune response of TH2 cells by inhibiting THE NF-KB signaling pathway, reduce the infiltration of inflammatory cells into lung nasal tissue, and reduce airway co-hyperreactivity to improve the clinical symptoms of asthma and play an immune protective role.

Publisher

Hindawi Limited

Subject

Radiology, Nuclear Medicine and imaging

Link

http://downloads.hindawi.com/journals/cmmi/2022/8990629.pdf

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1. Retracted: Investigation of the Immunoprotective Effect of Zinc on Ovalbumin Induced BALB/C Male Mice Based on NF-KB Signaling Pathway;Contrast Media & Molecular Imaging;2023-07-26

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