Affiliation:
1. BUASMV “King Michael I of Romania”, Faculty of Veterinary Medicine, Department of Toxicology, Calea Aradului, No. 119, Timisoara 300645, Romania
2. BUASMV “King Michael I of Romania”, Faculty of Veterinary Medicine, Depts. of Pharmacology and Pharmacy, Calea Aradului, No. 119, Timisoara 300645, Romania
3. BUASMV “King Michael I of Romania”, Faculty of Agriculture, Department of Chemistry, Calea Aradului, No. 119, Timisoara 300645, Romania
4. BUASMV “King Michael I of Romania”, Faculty of Bioengineering of Animal Resources, Department of Ecology and Environmental Protection, Calea Aradului, No. 119, Timisoara 300645, Romania
5. BUASMV “King Michael I of Romania”, Faculty of Agriculture, Department of Environmental Engineering, Calea Aradului, No. 119, Timisoara 300645, Romania
Abstract
Background. Quercetin’s role in the homeostasis of certain trace elements in dyslipidemia induced in mice was assessed. Methods. Forty BALB/c mice were allocated into 4 groups as follows: control; HFD, received fat diet; HFD + Q group, received HFD +500 mg/L quercetin; and blank control (Q)—normal food + 500 mg/L quercetin in drinking water. Results. By analyzing the values of total proteins, albumins, cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and the levels of several trace elements in blood and organs, we perceived a statistically significant increase (
,
) of TP, ALB, TC, TGE, and LDL-c. A nonsignificant decrease was ascertained to HDL-c value in the HFD and quercetin groups (
). In the HFD group, all analyzed elements in the kidney and spleen increased, also Cu, Li, Mg, Mn, Pb, and of B, Ba, Cr, Cd, Cu, Fe, Li, Mn, Ni, Pb, and Zn in the heart increased, but furthermore, Ag, B, Ba, Cd, Cr, Fe, Ni, and Zn in blood, Ag and Zn in the liver, and Cd in the spleen decreased. In the HFD group who received quercetin, elements (except B) were decreased in kidney and liver, also increased Ag, Ba, Cr, Fe, Li, Ni, Zn in blood, but similarly, Ag, B, Ba, Cd, Cu, Mn, and Pb declined in the spleen and heart. Conclusions. Results proved the quercetin beneficial role.
Funder
Research Institute for Biosecurity and Bioengineering Timisoara
Subject
Complementary and alternative medicine