Essential Oil Constituents ofTanacetum cilicicum: Antimicrobial and Phytotoxic Activities

Abstract

Aerial parts ofTanacetum cilicicumwere hydrodistillated for 3 h using Clevenger. Essential oil (EO) yield was 0.4% (v/w). According to the GC/MS analyses, EO ofT. cilicicumconsisted of monoterpenes [α-pinene (2.95 ± 0.19%), sabinene (2.32 ± 0.11%), and limonene (3.17 ± 0.25)], oxygenated monoterpenes [eucalyptol (5.08 ± 0.32%), camphor (3.53 ± 0.27%), linalool (7.01 ± 0.32%),α-terpineol (3.13 ± 0.23%), and borneol (4.21 ± 0.17%)], and sesquiterpenes [sesquisabinene hydrate (6.88 ± 0.41%), nerolidol (4.90 ± 0.33%),α-muurolol (4.57%  ± 0.35), spathulanol (2.98 ± 0.12%), juniper camphor (2.68 ± 0.19%), (-)-caryophyllene oxide (2.64 ± 0.19%), 8-hydroxylinalool (2.62 ± 0.15%), andΔ-cadinene (2.48 ± 0.16%)]. In the antimicrobial assay, MIC/MBC values of the EO were the most significant onB. subtilis(0.39/0.78 µL/mL) andB. cereus(0.78/1.56 µL/mL).The most prominent phytotoxic activities of the EO were observed onL. sativa,L. sativum, andP. oleracea. The results of the present study indicated that EO ofT. cilicicumincludes various medicinally and industrially crucial phytoconstituents that could be in use for industrial applications. The finding of this study is the first report on this species from the East Mediterranean region.