Review on Silver Nanoparticle Synthesis Method, Antibacterial Activity, Drug Delivery Vehicles, and Toxicity Pathways: Recent Advances and Future Aspects

Author:

Lekha D. Chandra1,Shanmugam R.2,Madhuri K.3,Dwarampudi L. Priyanka4,Bhaskaran Mahendran5,Kongara Deepak1,Tesfaye Jule Leta67,Nagaprasad N.8ORCID,Bhargavi V. L. Nirmal9,Krishnaraj Ramaswamy710ORCID

Affiliation:

1. Department of Pharmaceutical Analysis, Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra Pradesh, India

2. TIFAC, CORE-HD, Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Nilgiris, Ooty, Tamil Nadu, India

3. Pacemach Tech Consultants, London, UK

4. Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Nilgiris, Ooty, Tamil Nadu, India

5. Department of Pharmaceutical, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

6. Department of Physics, College of Natural and Computational Science, Dambi Dollo University, Ethiopia

7. Centre for Excellence-Indigenous Knowledge, Innovative Technology Transfer and Entrepreneurship, Dambi Dollo University, Ethiopia

8. Department of Mechanical Engineering, ULTRA College of Engineering and Technology, Madurai, 625104 Tamilnadu, India

9. Department of Chemistry, Sri Venkateswara College of Engineering and Technology, 517004, Chittoor, Andhra Pradesh, India

10. Department of Mechanical Engineering, College of Engineering and Technology, Dambi Dollo University, Ethiopia

Abstract

Silver nanoparticles in the range from 1 to 100 nm are widely used in industrial applications as catalysis, electronics, and photonics, and they have unique properties such as optical, electrical, and magnetic characteristics that can be used as antimicrobial, biosensor textile, cosmetics, composite fibers, and electronic components and to amend shelf life of food substances. The main objective of the present review was to focus on formulation methods of silver nanoparticles with recent advances and future aspects. Silver nanoparticle shows very high potential towards biological applications. Several physicals, chemical, and various biological techniques have been employed to synthesize and stabilize silver nanoparticles. For the manufacture of silver nanoparticles, multiple methods, including chemical simplification with different natural and inorganic decreasing agents, physicochemical reduction, electrochemical procedures, and radiolysis, are employed. Silver nanoparticles are the single most manufacturer-identified material that can be used in all nanotechnology products. They can be used in food packing polymers to enhance the shelf lifespan. The present review is aimed at different types of synthesis and details of silver nanoparticles used as drug delivery vehicles, antibacterial activity, toxicity, recent advances, and future aspects.

Publisher

Hindawi Limited

Subject

General Materials Science

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