Update on Anaplastic Thyroid Carcinoma: Morphological, Molecular, and Genetic Features of the Most Aggressive Thyroid Cancer-Reference-Cited by-同舟云学术

Update on Anaplastic Thyroid Carcinoma: Morphological, Molecular, and Genetic Features of the Most Aggressive Thyroid Cancer

Published:2014 Issue: Volume:2014 Page:1-13
ISSN:1687-8337
Container-title:International Journal of Endocrinology
language:en
Short-container-title:International Journal of Endocrinology

Author:

Ragazzi Moira¹,Ciarrocchi Alessia²,Sancisi Valentina²^ORCID,Gandolfi Greta²^ORCID,Bisagni Alessandra¹^ORCID,Piana Simonetta¹

Affiliation:

1. Pathology Unit, IRCCS-Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42123 Reggio Emilia, Italy

2. Laboratory of Translational Research, Research and Statistic Infrastructure, Arcispedale S. Maria Nuova-IRCCS, 42123 Reggio Emilia, Italy

Abstract

Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer. It shows a wide spectrum of morphological presentations and the diagnosis could be challenging due to its high degree of dedifferentiation. Molecular and genetic features of ATC are widely heterogeneous as well and many efforts have been made to find a common profile in order to clarify its cancerogenetic process. A comprehensive review of the current literature is here performed, focusing on histopathological and genetic features.

Publisher

Hindawi Limited

Subject

Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://downloads.hindawi.com/journals/ije/2014/790834.pdf

Reference89 articles.

1. Anaplastic Thyroid Carcinoma: A Study of 70 Cases

2. Anaplastic carcinoma of the thyroid: A clinicopathologic study of 121 cases

3. Small cell carcinoma of the thyroid

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