Affiliation:
1. Department of Chemistry and Biochemistry, University of Pune, Pune 411 007, India
Abstract
The coordinatively unsaturated copper (II) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2-
butene with different ancillary anions were synthesized which can bind to copper centers of
tyrosinase enzyme. The compounds were found to exhibit inhibitory activities against
mushroom tyrosinase and the nature and extent of inhibition is modulated according to the
type of ancillary anions.
Subject
Inorganic Chemistry,Drug Discovery,Pharmacology,Toxicology
Cited by
10 articles.
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