Solvent-Free Microwave Synthesis of Aryloxypropanolamines by Ring Opening of Aryloxy Epoxides-Reference-Cited by-同舟云学术

Solvent-Free Microwave Synthesis of Aryloxypropanolamines by Ring Opening of Aryloxy Epoxides

Published:2009-03-04 Issue: Volume:2009 Page:1-5
ISSN:1687-6865
Container-title:Research Letters in Organic Chemistry
language:en
Short-container-title:Research Letters in Organic Chemistry

Author:

Kureshy Rukhsana I.¹,Ahmad Irshad²,Pathak Kavita¹,Khan N. H.¹,Abdi Sayed H. R.¹,Bajaj H. C.¹,Suresh Eringathodi³^ORCID

Affiliation:

1. Discipline of Inorganic Materials and Catalysis, Central Salt and Marine Chemicals Research Institute (CSMCRI), Council of Scientific and Industrial Research (CSIR), G. B. Marg, Bhavnagar 364 002, Gujarat, India

2. Leibniz-Institute for Surface Modification e.V. (IOM), Permoserstraße 15, 04318 Leipzig, Germany

3. Analytical Science Division, Central Salt and Marine Chemicals Research Institute (CSMCRI), G. B. Marg, Bhavnagar 364 002, Gujarat, India

Abstract

The ring opening reaction of aryloxyepoxides with isopropylamine under solvent-free microwave irradiation produced therapeutically useful -blockers-aryloxypropanolamines in excellent yield (up to 98%) in 10 minutes which is considerably less than the time taken in classical heating ( hours).

Publisher

Hindawi Limited

Link

http://downloads.hindawi.com/archive/2009/109717.pdf

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