Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety

Author:

Yu Xuetong1,Lan Wenjun1,Chen Meihang2,Xu Su1,Luo Xiaoxi1,He Shuhong1,Chen Haijiang1,Fei Qiang1ORCID,Wu Wenneng1ORCID

Affiliation:

1. Food and Pharmaceutical Engineering Institute, Guiyang University, Guiyang 550003, China

2. Material and Chemistry Engineering Institute, Tongren College, Tongren 554300, China

Abstract

Seventeen novel N-phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea (B. dothidea), and Botrytis cinerea (B. cinerea) at 50 μg/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda (S. frugiperda) and Mythimna separata (M. separata) at 500 μg/mL than chlorantraniliprole.

Funder

Science and Technology Fund Project of Guizhou

Publisher

Hindawi Limited

Subject

General Chemistry

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