Cooccurrence of Darier’s Disease and Epilepsy: A Pediatric Case Report and Review of the Literature-Reference-Cited by-同舟云学术

Cooccurrence of Darier’s Disease and Epilepsy: A Pediatric Case Report and Review of the Literature

Published:2014 Issue: Volume:2014 Page:1-3
ISSN:2090-6803
Container-title:Case Reports in Pediatrics
language:en
Short-container-title:Case Reports in Pediatrics

Author:

Celik Tamer¹,Celik Umit²,Donmezer Cigdem²,Komur Mustafa¹,Tolunay Orkun²,Demirtürk Pelin³

Affiliation:

1. Pediatric Neurology, Adana Numune Research and Training Hospital, Adana, Turkey

2. Pediatrics, Adana Numune Research and Training Hospital, Adana, Turkey

3. Pathology Department, Adana Numune Research and Training Hospital, Adana, Turkey

Abstract

Darier’s disease is a skin disorder characterized by multiple eruptions of hyperkeratosis or crusted papules at seborrheic areas with histologic acantholysis and dyskeratosis. It is caused by mutations in a single gene, beingATP2A2and that is expressed in the skin and brain. The cooccurrence of various neurologic and psychiatric diseases with Darier's disease has been reported frequently in literature. They include mood disorders, epilepsy, encephalopathy, and schizophrenia. In this study, we report a pediatric case with the cooccurrence of Darier’s disease and epilepsy. We also revised current English literature on this topic.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/journals/cripe/2014/831398.pdf

Reference21 articles.

1. Spectrum of novel ATP2A2 mutations in patients with Darier's disease

2. The phenotype of Darier's disease: penetrance and expressivity in adults and children

3. Darier-White disease: A review of the clinical features in 163 patients

4. ATP2A2 Mutations in Darier's Disease and Their Relationship to Neuropsychiatric Phenotypes