Integrated Chinese Herbal Medicine and Western Medicine on the Survival in Patients with Colorectal Cancer: A Retrospective Study of Medical Records-Reference-Cited by-同舟云学术

Integrated Chinese Herbal Medicine and Western Medicine on the Survival in Patients with Colorectal Cancer: A Retrospective Study of Medical Records

Published:2020-01-13 Issue: Volume:2020 Page:1-10
ISSN:1741-427X
Container-title:Evidence-Based Complementary and Alternative Medicine
language:en
Short-container-title:Evidence-Based Complementary and Alternative Medicine

Author:

Yeh Ming-Hsien¹²,Chiu Hung-Pin³,Wu Mei-Chun³,Koo Malcolm⁴⁵^ORCID,Lin Nai-Wei⁶^ORCID,Liao Kou-Kai³,Yeh Chia-Chou²⁷^ORCID,Li Te-Mao¹^ORCID

Affiliation:

1. Graduate Institute of Chinese Medicine, China Medical University, Taichung 40402, Taiwan

2. Department of Chinese Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Chiayi 62247, Taiwan

3. Department of Information Management, Nanhua University, Dalin, Chiayi 62249, Taiwan

4. Graduate Institute of Long-term Care, Tzu Chi University of Science and Technology, Hualien 97005, Taiwan

5. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario M5T 3M7, Canada

6. Institute of Computer Science and Information Engineering, National Chung Cheng University, Minxiong, Chiayi 621, Taiwan

7. School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien 97004, Taiwan

Abstract

Recent studies suggested that Traditional Chinese Medicine could play a beneficial role in conventional cancer treatment. The aim of this retrospective cohort study was to investigate the effect of Chinese herbal medicine (CHM) combined with Western medicine on the survival of patients with colorectal cancer. A retrospective cohort study was conducted on patients with newly diagnosed colorectal cancer identified from the Dalin Tzu Chi Hospital Cancer Registry Database in 2004–2014. Combining with the medical records of the study hospital, patients were classified into CHM users and CHM nonusers. Kaplan–Meier analyses and Cox proportional hazards regression analyses were used to investigate the survival between CHM users and CHM nonusers. A total of 535 patients with colorectal cancer were included in the study with 147 of them were CHM users. The log-rank test for Kaplan–Meier survival curve revealed a statistically significant difference between the survival of CHM users and CHM nonusers (P=0.006). Results from multivariate Cox regression analysis showed that CHM use was significantly associated with better survival (adjusted hazard ratio = 0.54, 95% CI = 0.38 to 0.77). In addition, the CHM formulae Jia Wei Xiao Yao San, Zhi Bah Di Huang Wan, Ping Wei San, and Qui Pi Tang were significantly associated with better survival. In conclusion, findings from this retrospective cohort study indicated that integrated CHM and Western medicine could improve survival in patients with colorectal cancer. Additional research on integrating TCM with Western medicine to improve cancer survival is warranted.

Funder

Tzu Chi Foundation School and Hospital Cooperation Program

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

Link

http://downloads.hindawi.com/journals/ecam/2020/4561040.pdf

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