Saliva as a Future Field in Psoriasis Research

Author:

Asa’ad Farah1ORCID,Fiore Marco2ORCID,Alfieri Aniello2ORCID,Pigatto Paolo Daniele Maria3,Franchi Chiara3,Berti Emilio4,Maiorana Carlo5ORCID,Damiani Giovanni346ORCID

Affiliation:

1. Department of Biomedical, Surgical & Dental Sciences, University of Milan, 20122 Milan, Italy

2. Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

3. Clinical Dermatology, Department of Biomedical, Surgical and Dental Sciences, IRCCS Galeazzi Orthopaedic Institute, University of Milan, 20126 Milan, Italy

4. Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita’ degli Studi di Milano, Unita’ Operativa di Dermatologia, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milano, Italy

5. Center for Jawbone Atrophies Policlinico Hospital, University of Milan School of Dentistry, 20122 Milan, Italy

6. Young Dermatologists Italian Network (YDIN), GISED, 24122 Bergamo, Italy

Abstract

Psoriasis is a skin inflammatory disease characterized by an increased body of comorbidities, including parodontopathy. Despite the visibility of skin lesions, prognostic biomarkers, related to disease monitoring and therapeutic effectiveness, are still missing. Although several markers have been studied, none of them has been identified as an independent prognostic factor. This concise review aims to summarize the current knowledge and results in saliva research applied to psoriasis. Combination of different markers could improve the prognostic prediction in patients with psoriasis. Future studies are needed to implement research on salivary biomarkers and their prognostic/therapeutic effects in the management of patients with psoriasis.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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