Identifying the Predictors of Short Term Weight Loss Failure after Roux-En-Y Gastric Bypass

Author:

Bahadori Effat1,Esfehani Ali Jafarzadeh2,Bahrami Leila Sadat1,Shadmand Foumani Moghadam Mohammad Reza3ORCID,Jangjoo Ali4,Nematy Mohsen1,Roghani Afshin5,Rezvani Reza1ORCID

Affiliation:

1. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2. Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

3. Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran

4. Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5. Institute for Sustainable Horticulture (ISH), 20901 Langley Bypass, Langley, BC V3A 8G9, Canada

Abstract

Introduction. Gastric bypass surgery is a gold standard therapy for severe obesity. This study aimed to evaluate anthropometric predictors for short-term excess weight loss (EWL) after Roux-en-Y gastric bypass surgery (RYGB) in a sample of severely obese patients. Materials and Methods. This cohort study was conducted on severely obese candidates for RYGB bariatric surgery in Mashhad, Iran. Indirect calorimetry, anthropometric measurements, and body composition data were collected before, one, and six months after RYGB. Results. Fifty-four participants (43, 79.6% women and 11, 20.4% men) with a mean age of 39.63 ± 9.66 years participated in this study. The mean total weight and BMI loss within six months were 32.89 ± 20.22 kg and 12.37 ± 7.34 kg/m2, respectively. The mean reduction in adipose tissue and fat-free mass was 24.49 kg and 7.46 kg, respectively. The mean resting metabolism rate (RMR) reduction at one and six months after RYGB was 260.49 kcal and 396.07 kcal, respectively. There was a significant difference in mean RMR between the baseline and one and six months after RYGB ( p < 0.001 ). There was no significant gender difference in mean weight and BMI loss percentage at six months post-RYGB ( p > 0.05 ). Baseline skeletal muscle mass (SMM), excess BMI loss (EBMIL) at first month after surgery, and baseline neck circumference (NC) could predict EWL six months after surgery. Conclusion. Reduced RMR shortly after RYGB may be due to FFM reduction. Some anthropometric and their acute changes after RYGB may predict the short-term EWL in RYGB patients.

Funder

Mashhad University of Medical Sciences

Publisher

Hindawi Limited

Subject

General Medicine

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Review on Predictors of Weight Loss in Moderate to Severe Obesity Treatment;Journal of Korean Medicine for Obesity Research;2023-12-31

2. The Influence of Pregnancy on Weight Loss After Previous Bariatric Surgery;Journal of Laparoendoscopic & Advanced Surgical Techniques;2023-10-01

3. Revisiting Resting Metabolic Rate: What is the Relation to Weight Fluctuations?;Current Obesity Reports;2023-09-27

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