Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles-Reference-Cited by-同舟云学术

Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles

Published:2017 Issue: Volume:2017 Page:1-11
ISSN:2090-9063
Container-title:Journal of Chemistry
language:en
Short-container-title:Journal of Chemistry

Author:

Khalil Ahmed M.¹^ORCID,Abdel-Monem Reham A.¹,Darwesh Osama M.²,Hashim Ahmed I.³,Nada Afaf A.¹,Rabie Samira T.¹

Affiliation:

1. Photochemistry Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, Egypt

2. Environmental Biotechnology and Nanotechnology, Agricultural Microbiology Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, Egypt

3. Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt

Abstract

Schiff-bases of chitosan (CS) and carboxymethyl chitosan (CMCS)/silver nanoparticles (AgNPs) have been synthesized, characterized, and evaluated as antimicrobial agents against two Gram +ve bacteria (Bacillus cereus and Staphylococcus aureus) and two Gram −ve bacteria (Escherichia coli and Pseudomonas aeruginosa) in addition to Candida albicans as a fungus. The in situ reactions of CS and/or CMCS with some pyrazole aldehyde derivatives in acidic media containing silver nitrate to yield silver nanoparticles loaded onto CS and CMCS/Schiff-bases were carried out. Characterizations of the prepared compounds via FTIR spectroscopy, SEM, TEM, and TGA were carried out. Schiff-bases/silver nanoparticles of CS and CMCS showed higher antimicrobial activity than the blank CS and CMCS. The presence of AgNO3 (3% wt%) displayed high antibacterial efficiencies with inhibition zones in the extent of 19–39 mm. TEM analysis showed that the size of the silver nanoparticles is in the range of 4–28 nm for the prepared nanocomposites.

Funder

National Research Centre

Publisher

Hindawi Limited

Subject

General Chemistry

Link

http://downloads.hindawi.com/journals/jchem/2017/1434320.pdf

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