Food Supplement 20070721-GX May Increase CD34+Stem Cells and Telomerase Activity

Author:

Lin Po-Cheng1,Chiou Tzyy-Wen2,Liu Po-Yen3,Chen Shee-Ping4,Wang Hsin-I5,Huang Pi-Chun5,Lin Shinn-Zong167,Harn Horng-Jyh89

Affiliation:

1. Center for Neuropsychiatry and Department of Neurosurgery, China Medical University Hospital, 2 Yuh-Der Road, Taichung 40447, Taiwan

2. Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

3. Graduate Institute of Chinese Medicine, China Medical University, Taichung 40447, Taiwan

4. Tzu Chi Stem Cells Centre, Buddhist Tzu Chi General Hospital, Hualien 97002, Taiwan

5. Department of Stem Cell Applied Technology, Gwo Xi Stem Cell Applied Technology, Hsinchu 30261, Taiwan

6. Graduate Institute of Immunology, China Medical University, Taichung 40447, Taiwan

7. Department of Neurosurgery, China Medical University Beigan Hospital, Yunlin 65152, Taiwan

8. Department of Pathology, China Medical University Hospital, 2 Yuh-Der Road, Taichung 40447, Taiwan

9. Department of Medicine, China Medical University, Taichung 40447, Taiwan

Abstract

Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34+cells, insulin-like growth factor 1 (IGF1), and telomerase activity, which are all markers related to aging. To control the quality of this food supplement, five active components were monitored. In total, we examined 44 individuals who took the food supplement from 1.2 months to 23 months; the average number of CD34+cells was almost 6-fold higher in the experimental group compared with the control group. Food supplement intake did not change serum IGF1 levels significantly. Finally, the average telomerase activity was 30% higher in the subjects taking this food supplement. In summary, our results suggest that the placental extract in the food supplement might contribute to rejuvenation and antiaging.

Funder

Taiwan Department of Health

Publisher

Hindawi Limited

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology,Molecular Medicine,General Medicine,Biotechnology

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