Falls and Fractures in the Elderly with Sinus Node Disease: The Impact of Pacemaker Implantation

Author:

Krasniqi Nazmi1,Segalada Diana1,Lüscher Thomas F.12,Lippuner Kurt3,Haegeli Laurent1,Steffel Jan1,Wolber Thomas1,Brunckhorst Corinna1,Holzmeister Johannes1,Hürlimann David1,Duru Firat12

Affiliation:

1. Clinic for Cardiology, University Hospital Zurich, Rämistrasse 100, B 8091 Zurich, Switzerland

2. Center for Integrative Human Physiology, University of Zurich, 8057 Zurich, Switzerland

3. Osteoporosis Unit, University Hospital and University of Bern, 3010 Bern, Switzerland

Abstract

Background. Falls and fractures in the elderly are among the leading causes of disability. We investigated whether pacemaker implantation prevents falls in patients with SND in a large cohort of patients.Methods. Patient demographics and medical history were collected prospectively. Fall history was retrospectively reconstituted from available medical records. The 10-year probability for major osteoporotic fractures was calculated retrospectively from available medical records using the Swiss fracture risk assessment tool FRAX-Switzerland.Results. During a mean observation period of 2.3 years after implantation, the rates of fallers and injured fallers with fracture were reduced to 15% and 6%, respectively. This corresponds to a relative reduction in the number of fallers of 75% (P<0.001) and of injured fallers of 63% (P=0.014) after pacemaker implantation. Similarly, the number of falls was reduced from 60 (48%) before pacemaker implantation to 22 (18%) thereafter (relative reduction 63%,P=0.035) and the number of falls with injury from 22 (18%) to 7 (6%), which corresponds to a relative reduction of 67%,P=0.013.Conclusion. In patients with SND, pacemaker implantation significantly reduces the number of patients experiencing falls, the total number of falls, and the risk for osteoporotic fractures.

Funder

Medtronic

Publisher

Hindawi Limited

Subject

Cardiology and Cardiovascular Medicine

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