Glu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human Diseases
Author:
Affiliation:
1. Department of Bioengineering, Harbin Institute of Technology at Weihai, Shandong 264209, China
2. Department of Mathematics, Harbin Institute of Technology at Weihai, Shandong 264209, China
Abstract
Funder
National Natural Science Foundation of China
Publisher
Hindawi Limited
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://downloads.hindawi.com/journals/bmri/2015/174050.pdf
Reference87 articles.
1. Aldehyde Dehydrogenase 2 Gene Targeting Mouse Lacking Enzyme Activity Shows High Acetaldehyde Level in Blood, Brain, and Liver after Ethanol Gavages
2. Possible Role of Liver Cytosolic and Mitochondrial Aldehyde Dehydrogenases in Acetaldehyde Metabolism
3. Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.
4. Deficiency in Mitochondrial Aldehyde Dehydrogenase Increases the Risk for Late-Onset Alzheimer's Disease in the Japanese Population
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