Magnetic Particle Imaging in Vascular Imaging, Immunotherapy, Cell Tracking, and Noninvasive Diagnosis

Author:

Chandrasekharan Prashant1ORCID,Kuo Renesmee1ORCID,Fung K. L. Barry1ORCID,Saayujya Chinmoy2ORCID,Bryan Jacob1ORCID,Yousuf Mariam1ORCID,Fellows Benjamin1ORCID,Colson Caylin1,Huynh Quincy2ORCID,Doyle Owen1ORCID,Hartley Allison1,Yousuf Khadija1,Goodwill Patrick3ORCID,Conolly Steven12ORCID

Affiliation:

1. Department of Bioengineering, Berkeley, University of California Berkeley, CA 94720, USA

2. Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA 94720, USA

3. Magnetic Insight, Alameda, CA, USA

Abstract

Magnetic particle imaging (MPI) is a new tracer-based imaging modality that is useful in diagnosing various pathophysiology related to the vascular system and for sensitive tracking of cytotherapies. MPI uses nonradioactive and easily assimilated nanometer-sized iron oxide particles as tracers. MPI images the nonlinear Langevin behavior of the iron oxide particles and has allowed for the sensitive detection of iron oxide-labeled therapeutic cells in the body. This review will provide an overview of MPI technology, the tracer, and its use in vascular imaging and cytotherapies using molecular targets.

Funder

National Science Foundation

Publisher

SAGE Publications

Subject

Condensed Matter Physics,Radiology, Nuclear Medicine and imaging,Biomedical Engineering,Molecular Medicine,Biotechnology

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