Serological Findings in a Child with Paroxysmal Cold Haemoglobinuria

Author:

Salido Eduardo J.1,Cabañas Valentín1,Berenguer Mercedes1ORCID,Macizo María I.2,García-Candel Faustino1,Pérez-López Raúl1,Moraleda Jose M.1ORCID

Affiliation:

1. Hematology Department, Hematopoietic Transplant and Cellular Therapy Unit, Virgen de la Arrixaca Clinical University Hospital, IMIB-Arrixaca, University of Murcia, Carretera Madrid-Cartagena, s/n, El Palmar, 30120 Murcia, Spain

2. Laboratory Medicine Department, Virgen de la Arrixaca Clinical University Hospital, IMIB-Arrixaca, University of Murcia, Carretera Madrid-Cartagena, s/n, El Palmar, 30120 Murcia, Spain

Abstract

PCH is a rare autoimmune hemolytic anemia (AIHA) but is one of the most common causes of AIAH in children. For the diagnosis, it is important to perform the appropriate methods of serological investigation and show the typical biphasic reaction. This is a case report of a child who presented with features of haemolysis and was diagnosed with PCH of this way.

Publisher

Hindawi Limited

Subject

General Medicine

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Hot and Cold;Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy;2023

2. How to use Donath-Landsteiner test to diagnose paroxysmal cold haemoglobinuria (PCH);Archives of disease in childhood - Education & practice edition;2021-08-25

3. Acute paroxysmal cold haemoglobinuria; a case report and literature review;Bangladesh Journal of Medical Science;2021-04-04

4. Hot and Cold;Immunohematology and Transfusion Medicine;2018

5. Diagnostic difficulties in a patient with paroxysmal cold haemoglobinuria and acute kidney injury;Central European Journal of Immunology;2017

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