Application of Platelet-Rich Fibrin and Bone Morphogenetic Protein for Full-Mouth Implant-Based Oral Rehabilitation in a Case of Mandibular Osteoradionecrosis

Author:

Moaddabi Amirhossein12,Soltani Parisa34ORCID,Yazdani Arman5ORCID,Nikbakht Mohammad Hossein5ORCID,Amani Beni Pardis5ORCID,Modabber Elahe5ORCID,Iaculli Flavia4ORCID,Spagnuolo Gianrico4ORCID

Affiliation:

1. Department of Oral and Maxillofacial Surgery, Dental Research Center, Mazandaran University of Medical Sciences, Sari, Iran

2. Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran

3. Department of Oral and Maxillofacial Radiology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

4. Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Naples, Italy

5. Student Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Osteoradionecrosis (ORN) is a debilitating complication following radiation therapy, which in the head and neck region, occurs most frequently in the mandible. Although ORN is rare, it is complex and multifactorial and requires appropriate management. Manipulation of bone in patients with head and neck cancers before radiotherapy can cause ORN. In this report, we aim to present successful insertion of four dental implants in the interforaminal segment combined with application of platelet-rich fibrin and bone morphogenetic protein in a 60-year-old male with stable ORN in the posterior regions of the mandible.

Publisher

Hindawi Limited

Subject

General Dentistry

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