Affiliation:
1. Department of Biosciences, Integral University, Kursi Road, Lucknow 226026, India
Abstract
The therapeutic value ofAegle marmelosCorrea (Rutaceae), commonly known as ‘‘Bael,’’ has been recognized as a component of traditional medication for the treatment of various human ailments. The plant, though, being highly explored, still lacks sufficient evidences for the best variety possessing the highest degree of medicinal values. The present study is focused on phytochemical screening of aqueous and methanolic leaf extracts of 18 varieties/accessions ofA. marmelos. The crude extracts ofA. marmelosrevealed the presence of several biologically active phytochemicals with the highest quantity of alkaloids, flavonoids, and phenols in Pant Aparna variety. The antibacterial efficacy was investigated against pathogenic bacterial strains and the highest inhibitory activity of aqueous extract was obtained againstS. epidermidis, whereas methanolic extract was found to be most potent againstS. aureusat 40 mg/mL concentration. However, in aqueous : ethanol, the best results were observed againstE. aerogenesfollowed byK. pneumoniaandS. epidermidis. The MIC of aqueous and methanol extract ofAegle marmelosranged from 10 mg/mL to 40 mg/mL whereas in aqueous : ethanol it ranged between 40 mg/mL and 160 mg/mL. The GC-MS analysis revealed the presence of many bioactive compounds such as flavonoids, alcohols, aldehydes, aromatic compounds, fatty acid methyl esters, terpenoids, phenolics, and steroids that can be postulated for antibacterial activity.
Funder
University Grants Commission
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
250 articles.
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