Synthesis, CP-MAS NMR Characterization, and Antibacterial Activities of Glycine and Histidine Complexes of Cd(SeCN)2and Hg(SeCN)2

Abstract

The synthesis and characterization of cadmium and mercury complexes of selenocyanate of the type [(L)M(SeCN)2] are described, where L is L-Histidine (His) or L-Glycine (Gly) and M is Cd2+or Hg2+. These complexes are obtained by the reaction of 1 equivalent of respective amino acids with metal diselenocyanate precursor in a mixture of solvents (methanol : water = 1 : 1). These synthesized compounds are characterized by analytical and various spectroscopic techniques such as elemental analysis (EA), IR,H,1andC13NMR in solution and in the solid state forC13andN15. Thein vitroantibacterial activities of these complexes have been investigated with standard type cultures ofEscherichia coli(MTCC 443),Klebsiella pneumoniae(MTCC 109),Pseudomonas aeruginosa(MTCC 1688),Salmonella typhi(MTCC 733), andStaphylococcus aureus(MTCC 737).