Affiliation:
1. Endocrine Metabolism Department, Anhui Provincial Children’s Hospital, Hefei 23000, Anhui, China
Abstract
Objective. To compare the clinical efficacy of different insulin administration methods and blood glucose monitoring methods in treating type 1 diabetes mellitus in children. Methods. Patients were divided into four groups: multiple daily injection (MDI) + fingertip blood glucose detection, continuous subcutaneous insulin infusion (CSII) + fingertip blood glucose detection, MDI + continuous glucose monitoring system (CGMS), and CSII + CGMS. After six months of treatment, followed by telephone and at least once a month in an outpatient clinic, insulin doses were adjusted according to the children’s blood glucose levels. Blood glucose control and the daily dose of insulin were compared among the four groups after treatment, and the incidence of hypoglycemia in each group was recorded during the treatment. We also compare the incidence of the adverse event among the four groups. Results. 6 months later, the levels of HbA1c, FBG, and two h PG in each group were lower than those before treatment. There were significant differences in HbA1c, two h PG, and the daily insulin dose among the four groups. There were differences in the frequency of hypoglycemia among all the groups. The frequency of hypoglycemia in groups C and D was lower than in group A. Conclusions. CSII was better than MDI, and the blood glucose monitoring effect of CGMS was better than the fingertip blood glucose detection. The patients treated with CSII combined with CGMS had the best clinical efficacy. The patients treated with CSII combined with CGMS had the lowest adverse events incidence.
Funder
Clinical Application of Electronic Ketone Meter in Children with Type 1 Diabetic Ketoacidosis
Subject
Complementary and alternative medicine
Reference20 articles.
1. Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus
2. Chloroquine as a promising adjuvant therapy for type 1 Diabetes Mellitus
3. International Diabetes Federation 2017
4. Analysis of the effect of targeted health education on blood glucose level and nursing satisfaction in children with type 1 diabetes who are re-visited and rehospitalized;X. Li;Chinese Medicine and Clinical,2021
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献